About Covaris

Covaris is a global leader in advanced sample preparation solutions, revolutionizing the field with its proprietary Adaptive Focused Acoustics (AFA)™ technology. Established with a commitment to precision and innovation, Covaris has set the industry standard for highly controlled and reproducible mechanical sample processing.

With a strong presence in genomics, proteomics, and drug discovery, Covaris instruments enable researchers to achieve optimal results in DNA/RNA shearing, tissue homogenization, and compound formulation. Covaris systems are widely recognized for their ability to deliver highly reproducible, contamination-free, and temperature-controlled sample preparation, ensuring superior downstream analysis.

Epigenetics & Chromatin Studies

  • Chromatin shearing for ChIP assays

Drug Discovery & Formulation

  • Encapsulation, compound dissolution, and particle size reduction

Forensics & Clinical Research

  • Extraction of nucleic acids and biomolecules from challenging samples

Advancing Research & Diagnostics

Covaris LE220R-plus and M220 systems deliver precise, reproducible DNA and RNA shearing using proprietary AFA technology. These platforms enhance sample prep efficiency, accelerate NGS workflows, and reduce turnaround time for both research and clinical applications.

AFA-energetics®

Non-contact, isothermal acoustic energy ensures precise and reproducible shearing.

Touchscreen Interface

Intuitive touchscreen control for streamlined operation and protocol setup.

Automated Water Management

Hands-free degassing and fill functions reduce manual intervention.

Simultaneous Processing

Run up to 8 samples in parallel for higher throughput.

Embedded RFID Reader

Ensures traceability and automation with RFID tube compatibility.

Application Areas

Covaris' cutting-edge technology supports a diverse range of research applications, including:

Next-Generation Sequencing

DNA/RNA shearing for library preparation

Proteomics & Metabolomics

Tissue homogenization and protein extraction

Epigenetics & Chromatin Studies

Chromatin shearing for ChIP assays

Drug Discovery & Formulation

Encapsulation, compound dissolution, and particle size reduction

Forensics & Clinical Research

Extraction of nucleic acids and biomolecules from challenging samples

Why Choose Covaris?

With over two decades of expertise, Covaris continues to empower researchers with state-of-the-art solutions that enhance accuracy, efficiency, and scalability in sample preparation. Whether in genomics, drug discovery, or clinical research, Covaris’ AFA™ technology ensures reliable and reproducible results for your most demanding applications.

DNA/RNA Shearing For NGS

Mechanical DNA/RNA shearing for reproducible results without GC bias or thermal damage powered by AFA.

Proteomics

Increased throughput and data reproducibility for protein extraction from diverse samples powered by AFA.

Cell Lysis

Gently disrupt mammalian cell membranes and abruptly disrupt bacterial cell walls using highly tunable AFA.

Automation

Automated sample preparation solutions for high-throughput biology including instrumentation, consumables, software integrations and more.