Twist Bioscience Solutions: Precision at the Core of Genomic Advancement

Twist Bioscience, founded in 2013 by Dr. Emily Leproust, provides a suite of advanced Next-Generation Sequencing (NGS) solutions, designed to support a wide range of genomic research applications. Their proprietary silicon-based DNA synthesis platform enables the production of high-fidelity DNA probes, offering increased sequencing efficiency and uniformity.

This cutting-edge technology ensures greater accuracy and higher sequencing depth, while also reducing costs, making it an ideal solution for researchers aiming to push the boundaries of genomic exploration.

Fixed and Custom Panels

  • Exome 2.0
  • Human Comprehensive Exome
  • Human Methylome Panel
  • Custom panel

Library Preparation

  • FlexPrep™ UHT Library Prep Kit
  • cfDNA Library Preparation Kit
  • Enzymatic Fragmentation Kit
  • Methylation Detection System

Reagents & Kits

  • - Fast Hybridization and Wash Kit
  • Standard Hybridization Reagent Kit
  • Universal Blockers

Application Areas

Twist Bioscience's Next-Generation Sequencing (NGS) solutions are designed to support a variety of applications across multiple scientific disciplines:

Genomic Research:

Twist’s NGS platforms enable the analysis of genetic variations, advancing research in human genetics and the study of rare diseases.

Cancer Genomics

Their sequencing tools help identify genetic mutations in tumors, contributing to personalized treatment strategies and targeted therapies in cancer research.

Clinical Diagnostics

Twist's NGS technologies are used for genetic testing, rare disease diagnostics, and prenatal screening, improving diagnostic accuracy and clinical decision-making.

Microbiome Research

Twist’s sequencing technologies support in-depth studies of the human microbiome, offering insights into its role in health and disease.

Agricultural and Biotechnological Applications

Twist's NGS solutions aid in agricultural genomics, enhancing crop traits, supporting GMO development, and optimizing livestock breeding strategies.

Higher Confidence in Variant Detection

Uniformity describes the read distribution along target regions of the genome. Uniform coverage reduces the amount of sequencing required to reach a sufficient depth of coverage for all regions of interest. Achieving the sequencing requirement for your application equates to higher confidence in variant detection.

Custom & Fixed Panels

Flexible, high-performance panels for targeted sequencing — from ready-to-use fixed panels to fully customizable designs tailored to your research needs.

Library Prep Solutions

Efficient, low-input workflows for whole genome, exome, and targeted sequencing — enabling high coverage and reproducibility across sample types.

NGS Kits & Reagents

Comprehensive kits and reagents to support every stage of your NGS workflow — optimized for precision, speed, and scalability.

Why Choose Twist Bioscience's?

Innovative synthetic DNA technology and customizable solutions designed to accelerate your genomic discoveries with precision and reliability.

Increased Depth

High-fidelity probes improve target coverage and sequencing depth significantly.

Reduced Over Sequencing

Uniformity reduces excess reads, saving time and sequencing resources efficiently.

Uniform Coverage

Consistent read distribution enables accurate, comprehensive variant detection across targets.

Higher Confidence in Variant Detection

Optimized depth ensures reliable variant calls for critical genomic applications.